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pharoah88
    14-Aug-2010 17:46  
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Ready for a world withOUT antibiotics?

A bedrock of modern medicine but in the near future, we’re going to have to learn to live without them

Sarah Boseley

In just a couple of generations, what once appeared to be miracle medicines have been beaten into ineffectiveness by the bacteria they were designed to knock out. Once, scientists hailed the end of infectious diseases. Now, the postantibiotic apocalypse is within sight.Lancet Infectious Diseases this week posed the question over a paper revealing the rapid spread of multi-drug-resistant bacteria.

Hyperbole? Unfortunately not.

The highly serious journal

“Is this the end of antibiotics?” it asked.

Doctors and scientists have not been complacent, but the paper by Professor Tim Walsh and colleagues takes the anxiety to a new level. Last September, Walsh published details of a gene he had discovered, called NDM1 (New Delhi Metallobeta-lactamase 1), which passes easily between types of bacteria and makes them resistant to almost all the powerful, last-line antibiotics called carbapenems.

This week’s paper revealed that NDM1 is widespread in India and has arrived as a result of global travel and medical tourism for, among other things, transplants, pregnancy and cosmetic surgery.

(The paper has triggered a storm of protest from India’s medical industry. Reports from India cited Indian doctors saying that the warnings about this drugresistant superbug were alarmist.)

Walsh disagrees: “This is potentially the end.

There are no antibiotics in the pipeline that have activity against NDM 1-producing enterobacteriaceae. We have a bleak window of maybe 10 years, where we are going to have to use the antibiotics we have very wisely, but also grapple with the reality that we have nothing to treat these infections with.”

And this is the optimistic view — based on the assumption that drug companies can and will get moving on discovering new antibiotics to throw at the bacterial enemy. Since the ’90s pharmaceutical companies have not shown a great deal of enthusiasm for difficult antibiotic research. Unlike with heart medicines, people take antibiotics for a week rather than life, and because resistance means the drugs become useless after a while, there is just not much money in it.

Dr Livermore, whose grandmother died for lack of infection-killing drugs in 1945, is director of the antibiotic resistance monitoring laboratory of the Health Protection Agency (HPA). Last year, the HPA put out an alert about NDM1, urging health professionals to report all suspect cases.

Livermore is far from sanguine about the future.

“A lot of modern medicine would become impossible if we lost our ability to treat infections,” he says. He is talking about transplant surgery, for instance, where patients’ immune systems have to be suppressed to stop them rejecting a new organ, leaving them prey to infections, and the use of immunosuppressant cancer drugs.

The era of antibiotics is coming to a close.

 
 
pharoah88
    14-Aug-2010 13:28  
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South Asia ‘superbug’ claims its first victim

BRUSSELS

Mr Denis Pierard, a microbiologist from AZ VUB hospital in Brussels where the victim had been treated since June, told Belgian media that the man was infected by the bacteria while being treated in a hospital in Pakistan.

“He was involved in a car accident in Pakistan. He was hospitalised with a leg injury and then repatriated to Belgium, but he was already infected,” the doctor said.

Despite receiving powerful antibiotics, the patient died.

According to a report on Belgian TV channel

The superbug — a bacterial gene called New Delhi metallo-lactamase-1 (NDM-1) — was first identified last year in a Swedish patient admitted to hospital in India.

Professor Peter Collignon, Canberra Hospital’s head of infectious diseases department, said the superbug has infected three Australians, including one patient who had plastic surgery in Mumbai.

These patients were just the “tip of the iceberg”, said Dr Collignon, adding: “There may well be more because it’s difficult to pick up this particular gene unless you’ve got sophisticated testing.”

British scientists sparked an angry response from India when they said “medical tourists” to the subcontinent were among 37 people who were found to be infected.

“We strongly refute the naming of the enzyme ... and also refute that hospitals in India are not safe for treatment including medical tourism,” the Indian Health Ministry said.

The gene, which is found in a number of different bacteria, produces an enzyme that renders even very strong antibiotics ineffective.

Dr Collignon blamed the new bugs on the “abuse” of antibiotics in medicine and also in agriculture, saying some countries used them on billions of chickens, which develop bacteria and are then consumed by humans.

The professor, who sits on World Health Organisation panels on antibiotics, called for a worldwide crackdown on antibiotic use along with a major hygiene campaign to stop the bugs spreading.

Singapore’s Health Ministry said there has not been any case reported locally to date: “Our hospitals have a robust surveillance and infection control system (eg stringent hand hygiene practices, etc) in place and we will continue to monitor the situation closely.

Cooperation from all is needed to stop germs from spreading. We can help by having good personal hygiene practices such as proper and frequent hand washing, and observing the strict visitation policy of hospitals to prevent cross infection.”— A Belgian man died from a drug-resistant “superbug” originating in South Asia, a doctor said on Friday. It is the first reported death from the bacteria, as fears it could spread worldwide were reinforced after three Australians who travelled to India were reportedly infected.RTBF, it was the second reported case of the bacteria in the country this year.

AFP, wi th addi tional rep orting by Esthe r Ng

 
 
pharoah88
    12-Aug-2010 14:27  
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BREATH TEST can identify different types of CANCER, say scientists

LONDON

Their preliminary results, printed in the

The sensor used gold nanoparticles to detect levels of so-called volatile organic compounds, measured in a few parts per billion, that became more elevated in cancer patients.

The device could provide an early warning system that flags the disease before tumours become visible in X-rays.

The study examined the breath of 177 volunteers, including healthy people and patients already diagnosed with different stages of the four types of cancer.

However, further tests with larger samples will be needed to determine the strength of the link between breath and cancer detection.

“These results are interesting and show that there is the potential to develop a single breath test to detect these cancers,” said Dr Lesley Walker of the CancerActive charity in the United Kingdom.

“Strengthening the methods for early diagnosis of cancer, as well as improved treatments will have a significant impact on cutting death rates,” she added.— Scientists working on a breath test to detect cancer said in research published yesterday that they are now able to identify different types of the disease.British Journal of Cancer monthly, showed that the sensors could distinguish whether a patient had lung, breast, bowel or prostate cancer, irrespective of age, gender or lifestyle.

AFP

 

 
pharoah88
    12-Aug-2010 10:44  
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Superbugs in UK

New bacteria from South Asia could spread worldwide, study warns

LONDON

Many hospital infections that were already difficult to treat have become even more impervious to drugs due to a recently-discovered gene that can jump across different species of bacteria.

Worryingly, the New Delhi metallo-beta-lactamase- 1 bacteria (NDM-1) are resistant even to carbapenems, a group of antibiotics often reserved as a last resort for treatment for multi-drug resistant bugs.

Researchers said the bugs had been brought into Britain by patients who travelled to India or Pakistan for cosmetic surgery.

In the new study, led by Cardiff University’s Timothy Walsh and Madras University’s Karthikeyan Kumarasamy, researchers set out to determine how common NDM-1 was in South Asia and Britain, where several cases had turned up.

They found 44 cases — 1.5 per cent of those screened — in Chennai, and 26 in Haryana, both in India. They also found the superbug in Bangladesh and Pakistan, as well as 37 cases in Britain.

NDM-1 was mostly found in E coli and K pneumoniae.

It was impervious to all antibiotics except two — tigecycline and colistin.

Crucially, the NDM-1 gene was found on DNA structures, called plasmids, that can be easily copied and transferred between bacteria, giving the bug “an alarming potential to spread and diversify”.

“Unprecedented air travel and migration allow bacterial plasmids and clones to be transported rapidly between countries and continents,” the authors said.

The emergence of these new strains could become a serious global health problem as the major threat shifts towards a broad class of bacteria, they warned.

Professor Walsh said “there are no new antibiotics that are going to be available in 10 years’ time”.— “Health tourists” flocking to South Asia have carried a new class of antibiotic-resistant superbugs to Britain, researchers reported yesterday, warning that the bacteria could spread worldwide.

AGENCIES

 
 
pharoah88
    09-Aug-2010 12:47  
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Image
 
 
pharoah88
    08-Aug-2010 16:39  
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Another PILL that could cause a revolution

That seems possible, for these pills are beginning to revolutionise abortion around the world, especially in poor countries. One result may be tens of thousands of women’s lives saved each year.

Five-sixths of abortions take place in developing countries, where poor sterilisation and training often make the procedure dangerous. Up to 70,000 women die a year from complications from abortions, according to the World Health Organisation.

But researchers are finding an alternative that is safe, cheap and very difficult for governments to restrict — misoprostol, a medication originally intended to prevent stomach ulcers.

“I feel like people must have felt when they discovered the nuclear bomb,” says Dr Beverly Winikoff, president of Gynuity Health Projects, a non-profit research institution on reproductive health. “This technology is world-shaking.”

This pharmaceutical approach is called “medical abortion”.

In the United States and Europe it typically consists of two sets of “M” pills. The first is mifepristone, formerly known as RU486, and then a day or two later the misoprostol.

Using the drugs in combination produces a miscarriage more than 95 per cent of the time in early pregnancy. But mifepristone is difficult to obtain in much of the world, because it is used only to induce abortions.

In contrast, misoprostol is very widely available and cannot easily be banned because it is also used for ulcers and can save the lives of women with postpartum haemorrhages.

Whatever one thinks of misoprostol for abortions, it also is a potential lifesaver for women who haemorrhage after childbirth.Could the decades-long global impasse over abortion worldwide be overcome — by little white pills costing less than US$1 ($1.35) each?

 

 
yummygd
    04-Aug-2010 22:13  
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i love him i hope its him but at this price??

operation_pesb      ( Date: 04-Aug-2010 15:36) Posted:

15:29:00 0.190 9,540,000 Buy Up


 

omg don't tell me it's reminser king again.

 
 
operation_pesb
    04-Aug-2010 15:36  
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15:29:00 0.190 9,540,000 Buy Up


 

omg don't tell me it's reminser king again.
 
 
snooty
    29-Jul-2010 18:34  
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now that fortis failed in their parkway bid, maybe they can consider healthway?! hahah...
 
 
pharoah88
    24-Jul-2010 16:39  
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DESIGNER  VIRGIN  may NOT  be  a  VIRGIN  ? ? ? ?

<>
Australian doctors warn against 'designer vagina' craze
Fri, Aug 01, 2008
AFP
 
 


SYDNEY - AUSTRALIAN doctors have raised concerns about clinics offering vaginal cosmetic surgery, warning the trend towards so-called 'designer vaginas' may be exploiting vulnerable women.

The Royal Australian and New Zealand College of Obstetricians and Gynaecologists said procedures being offered included 'vaginal rejuvenation, revirgination, designer vaginoplasty and G-spot amplification'.

'What is involved in these procedures is often unclear since recognised clinical nomenclature is not being used,' it said in a position paper released this week.
 

 
pharoah88
    24-Jul-2010 16:35  
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MARRiES  ONE  WIFE  GETS  TWO  VIRGINS



Sun, May 09, 2010
The New Paper

Woman discovers she has two vaginas


By SHREE ANN MATHAVAN

IT was her first pap smear test and the Singaporean, in her mid-twenties, didn't expect any surprises. After all, she is young and healthy.

But what was to have been a routine five-minute check-up last month turned complicated - she discovered she had two vaginas. The discovery was also a first for her doctor.

Dr Chee Jing Jye, the medical director at The Obstetrics & Gynaecology Centre at Paragon Medical, had never encountered such a case in her 13 years of practice.

The discovery was made after the young woman was physically examined and had a 3-D ultrasound scan for abnormalities in the womb.

Fortunately, despite having two vaginas and two cervixes, her womb was fine. Still, the news came as a blow for the woman, said DrChee.

The distraught woman declined to be interviewed by The New Paper. Dr Chee said that one of the first questions she asked was: "Am I normal?"

The doctor, who is in her 30s, assured her that her condition isn't life-threatening and will not have a major impact on her life.

She told The New Paper: "Theoretically, the chances of her getting pregnant in the future should not be much of a problem."
 
 
pharoah88
    28-Jun-2010 12:12  
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Healthway Medical

19.5 cents | Buy

Shares gained 2.6 per cent to 19.5 cents, holding near 52-week high of 21 cents set last week.

DMG, has “Buy” call with 30 cents target, saying outlook favourable as healthcare group continues to make inroads in China using proceeds from placement of shares to World Bank’s International Finance Corp, other investors carried out earlier this year.

 
 
pharoah88
    16-Jun-2010 08:55  
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HEATHWAY MEDICAL’S trading volumes jumped today after investors caught on to former remisier king Peter Lim's recent purchases of the stock. 


His interest in Healthway came under the spotlight after open market purchases via investment vehicle Kestrel Capital on 2 Jun bumped his deemed stake above 5%.

Latest purchases in the owner of Singapore’s largest network of private medical centers and clinics upped his deemed stake to 7.21% as at 10 Jun.


Never mind that Heathway’s net profits contracted 63.9% year on year for the first quarter of FY2010 --- its trading volumes surged tenfold overnight thanks to investor interest spurred by the smart money move.

 

128 million shares changed hands today, the highest since Jan this year.

The company generated net profits of S$1.36 million for 1Q2010.

Revenues for 1Q2010 were S$22.2 million, down 6.3% year-on-year. However, net margins fell due to an increase in operating costs, which include overheads, new doctors hires and start-up expenses in its new centres.
In the past 6 months, Healthway started several new centres offering family medicine and specialist services, namely ear, nose and throat surgery, eye surgery, general surgery, cardiology, sports medicine, psychiatry, paediatric pulmonology, paediatric endocrinology, paediatric neurology and child psychology.

The stock last closed at 20 cents, up 25% on steady trend compared to two weeks ago when Peter Lim's interest was made public.

The stock may already be at an estimated 22x PE for the current year (compared to 19x sector average), but DMG’s Lynette Tan has a ‘Buy’ call on the stock with target price at 30 cents.

Analysts like Healthway for its expansion plans.

It aims to double the total number of clinics in Singapore (including 60 specialist clinics) in the next 5 years to 200.  Of this total, the number of primary healthcare clinics (including 20 dental practices) is expected to grow from 70 to 140.

It also plans to have a total of 8 medical centers in Shanghai, of which 6 are operational by this year.

Image
Ernest Lim, CFA, CPA

Ernest Lim, CFA, CPA, a remisier with CIMB-GK Securities, said: "There has been much trading interest in Healthway post Mr Lim Eng Hock’s (better known as Peter Lim) announcement that he has become a substantial shareholder of Healthway in early June. In addition, the partial take over bid of Parkway spurs interest in healthcare stocks. However, investors should do their due diligence before jumping onto the bandwagon of healthcare stocks, as they have diverse fundamentals and trading at different valuations."

 
 
Sporeguy
    15-Jun-2010 22:43  
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  31 Dec 09 price S$ Market cap S$ m                       PE (x)
2008             2009F           2010F
Parkway Holdings 2.92 3301.2 94.8 34.9 36.3
Raffles Medical 1.45 753.4 23.9 19.7 17.3
Thomson Medical Centre 0.69 201.5 17.7 15.8 14.2
Health Management 0.10 48.1 -110.6 N.A. N.A.
Pacific Healthcare 0.11 30.9 -2.6 N.A. N.A.
Healthway Medical 0.135 186.9 19.6 11.8 10.1
Average     7.1 20.6 19.5
Source: DMG & Partners
 
 
pharoah88
    15-Jun-2010 18:09  
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Healthway (5NG)              2010 JUNE 15  Tuesday 
Day Hi 0.205     Last 
0.200   vol 128,444,000
Day Lo 0.190    Chng
0.010



Tim. & SaleslTrad. SummarylQu.u. Tmack;0]

16:59:41 
16:59:33
16:59:18
16:58:01
16:5704
16:57:04
16:57:03
16:57:03
16:57:02
1657:01
16:56:58
16:56:44
16:56:27
16:56:06
16:55:56
16:5547
16.55:43
16:55:16
16:54:02



Trade Size               Bid-Ask
16:59:41 

0.200    500,000  Sold To Buyer
0.200      20,000  Sold To Buyer
0.200      22,000  Sold To Buyer
0.200    250,000  Sold To Buyer
0.200      20,000  Sold To Buyer

0.200    395,000  Bought From Seller
0.200      25,000  Bought From Seller
0.200 1,000,000  Bought From Seller
0.200    220,000  Bought From Seller
0 200 1,500,000  Bought From Seller
0.200    100,000  Bought From Seller
0.200 1,000,000  Bought From Seller
0.200      50,000  Bought From Seller
0.200      10,000  Bought From Seller
0.200    100,000  Bought From Seller
0.200    500,000  Bought From Seller
0.200    100,000  Bought From Seller
0.200    150,000  Bought From Seller
0.200    100,000  Bought From Seller





pharoah88      ( Date: 15-Jun-2010 17:56) Posted:



PETER LIM  is an INfamous  BRAND  for  his 

PiCKING  of  MULTi-BAGGERS

He PAiD S$2.50  for  WiLMAR  [HiGH  S$7.29]    3 BAGGER

He PAiD S$0.15  for  HEALTHWAY   [TARGET  S$0.45 ?]   3  BAGGER ?

 

 
pharoah88
    15-Jun-2010 17:56  
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PETER LIM  is an INfamous  BRAND  for  his 

PiCKING  of  MULTi-BAGGERS

He PAiD S$2.50  for  WiLMAR  [HiGH  S$7.29]    3 BAGGER

He PAiD S$0.15  for  HEALTHWAY   [TARGET  S$0.45 ?]   3  BAGGER ?
 
 
pharoah88
    15-Jun-2010 17:49  
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RESEARCH ALERT-DMG reiterates 'Buy' on Healthway Medical

SINGAPORE, June 7 (Reuters) - Following is a list of

Singapore stock price target changes and rating changes on

Monday.

 

COMPANY RIC BROKER RATING (PVS) TARGET PRICE (PVS)

HEALTHWAY MEDICAL

DMG (BUY) TARGET S$0.30 

 



pharoah88      ( Date: 08-Jun-2010 15:35) Posted:

<>
Peter LIM raises Healthway Medical stake
Lee Yen Nee
Tue, Jun 08, 2010
The Straits Times
 
  


 

FORMER remisier king Peter Lim has become a substantial shareholder in Healthway Medical by increasing his stake from 4.96 per cent to 6.03 per cent.

 

Last Wednesday, Mr Lim bought 14.56 million shares on the open market through his firm Kestrel Capital Partners. Prior to this purchase, he held 90.78 million shares, or 4.96 per cent.

 

Click here to find out more!
He paid 15 cents apiece, a price which works out to $2.18 million for the purchase.

 
 
pharoah88
    15-Jun-2010 17:44  
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$ Healthway Symbol:
5NG
Currency:
Singapore Dollar
Last: 0.2 + 0.01 Vol (K): 128444.0
Trading
Updated Time 15-Jun 17:05
Open 0.19 High 0.205 Low 0.19
Prev Close 0.19 Buy - Sell -
Volume(K) 128444.0 Buy Vol(K) - Sell Vol(K) -
52 Wk High 0.19 52 Wk Low 0.1 52 Wk Avg Vol 8568.893
All Time High 0.27 All Time Low 0.05    
Comments Near 52 wk high

*Reporting Currency in SGD
Important: ShareJunction obtains our finance data from a third party. Check financial year before use. EPS values are recorded up to two decimal points.
Financials
Date Updated 31-May-2010 Financial Year 31-Dec-2009
Current Year Profit
(After Tax) $'000,000
15.238 Previous Year Profit
(After Tax) $'000,000
9.555
Net Asset Per Share -0.01 Turnover $'000,000 225.01
Current Year EPS
(After Interest and Tax)
0.01 Previous Year EPS
(After Interest and Tax)
0.01
PE Ratio (After Tax) 15.0 Times Covered 4.6
Price (at update time) 0.15 Dividend Yield 0.01

*Technical Analysis Information is updated Daily
Technicals
RSI 76.82 Williams %R 0.0
Comments (RSI) Overbought Comments (W%R) Overbought

Intraday Chart

 
 
 
pharoah88
    15-Jun-2010 15:17  
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In this 21st Century,  Sweet Young Things [SYTs] are in demand.
 
 
pharoah88
    15-Jun-2010 14:55  
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who would want medical services full of RAFFLE(S) ? ? ? ?

pharoah88      ( Date: 15-Jun-2010 14:50) Posted:

raf·fle  (rfl)
n.
Rubbish; debris.

[Probably from French rafle, act of seizing, from Old French; see raffle1.]

The American Heritage® Dictionary of the English Language, Fourth Edition copyright ©2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.


 
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